PERSISTENCE AND INTRA-HOST GENETIC EVOLUTION OF ZIKA VIRUS INFECTION IN SYMPTOMATIC ADULTS: A SPECIAL VIEW IN THE MALE REPRODUCTIVE SYSTEM

Persistence and Intra-Host Genetic Evolution of Zika Virus Infection in Symptomatic Adults: A Special View in the Male Reproductive System

We followed the presence of Braces Zika virus (ZIKV) in four healthy adults (two men and two women), for periods ranging from 78 to 298 days post symptom onset.The patients were evaluated regarding the presence of the virus in different body fluids (blood, saliva, urine and semen), development of immune responses (including antibodies, cytokines an

read more

Microglia-mediated demyelination protects against CD8+ T cell-driven axon degeneration in mice carrying PLP defects

Abstract Axon degeneration and functional decline in myelin diseases are often attributed to loss of myelin but their relation is not fully understood.Perturbed myelinating glia can instigate chronic neuroinflammation and contribute to demyelination and axonal damage.Here we study mice with distinct defects in the proteolipid protein 1 gene that de

read more